COVAXI-2 (Haematological diseases - RECRUITMENT: OPEN)

Project Title

Official Title

SARS-CoV-2 (COVID-19) vaccination and the immune responses in patients with haematological malignancy and other immune deficiency.

Project Summary

This is an observational Cohort study to assess the immune response to the SARS-CoV-2 vaccination and the prevalence of clotting related antibodies in haematology and other immunosuppressed patients.

Blood Disorder

Haematological diseases

Patient Recruitment Details

Patient recruitment status: open

Number of patients (Globally)

300

Latest

DNA Day 2024

April 25 is DNA Day which provides a platform to acknowledge the importance of genetic research into new treatment options for life-threatening hereditary blood disorders.
Family Fun Day! Saturday 13 April

Kathryn and her Run for a Reason team are hosting a FAMILY FUN DAY this Saturday, 13th April to raise funds for the their running team - in memory of her son, Graham Derrick Wild.
Blood clot awareness

Raising awareness about blood related health issues
World Haemophilia Day 2024

April 17 is World Haemophilia Day which aims to raise awareness of haemophilia and other bleeding disorders. The World Federation of Hemophilia estimates that over 75% of people living with haemophilia worldwide have not yet been identified and diagnosed.

GO43073 (Multiple Myeloma - RECRUITMENT: commencing soon)
ISIS 702843 (Polycythemia vera - RECRUITMENT: OPEN)

This study will evaluate Sapablursen in patients with polycythemia vera.
RUBY-4 (Autoimmune cytopenias - RECRUITMENT: OPEN)

This study is an open-label study of Povetacicept in subjects with autoimmune cytopenias.
MAGNOLIA (Cancer-associated VTE - RECRUITMENT: OPEN)

This is a study comparing Abelacimab to Dalteparin in the treatment of gastrointestinal/genitourinary cancer and associated venous thromboembolism.
ASTER (Cancer-associated VTE - RECRUITMENT: OPEN)

This study will compare treatment with Abelacimab to apixaban on venous thromboembolism recurrence and bleeding in patients with cancer associated VTE.
MAHOGANY (Follicular or Marginal Zone Lymphoma - RECRUITMENT: OPEN)

This study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R^2) in participants with relapsed/refractory (R/R) follicular lymphoma (FL).
EPCORE DLBCL-2 (B-cell lymphoma - RECRUITMENT: OPEN)

This study is to assess the change in disease activity of epcoritamab when combined with intravenous and oral rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (R-CHOP) or R-CHOP in adult participants with diffuse large b-cell lymphoma.
BRUIN-CLL-314 (Chronic Lymphocytic Leukaemia/Small Lymphocytic Lymphoma - RECUITMENT: OPEN)

This study is to compare the efficacy and safety of pirtobruitinib to ibrutinib in participants with chronic lymphocytic leukaemia / small lympocytic lymphoma.
EXCALIBER-RRMM (Multiple Myeloma - RECRUITMENT: OPEN)

A Phase 3 study comparing the efficacy and safety of IberDd versus DVd in participants with relapsed or refractory multiple myeloma (RRMM).
ADVANCE SC+ (Thrombocytopenia - RECRUITMENT: CLOSED)

A Phase 3 study to evaluate the safety and efficacy of efgartigimod PH20 subcutaneous in adult patients with primary immune thrombocytopenia

What is thrombosis?

Click here to learn more about thrombosis.
What are DVT & PE?

Click here to learn more about DVT and PE.
Travel and Thrombosis

Click here to learn about how travel can increase your risk of developing dangerous blood clots.
Work and Thrombosis

Click here to learn more about how work can increase your risk of thrombosis, and how to prevent it.
Contraception and Thrombosis

Click here to learn more about how certain contraceptives can increase your risk of dangerous blood clots.
Antiphospholipid Antibody Syndrome

Click here for information about antiphospholipid antibody syndrome and how it can lead to thrombosis.
Chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a blood cancer which affects the bone marrow and white blood cells. This type of blood cancer is the most prevalent subtype of leukaemia in Western countries.
PCOS and thrombosis

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder and one of the most common endocrine system and reproductive disorders among women. Here we provide some information regarding its association with thrombosis.
Inherited Thrombophilias

Click here for information about genetic conditions that can increase the chances of thrombosis.
Investigators

Let's make blood disorders a thing of the past! Donate today!

Your continuous support and dedicated following of PBI is transforming the lives of people suffering from blood-related health conditions. Every amount is vital to our research, no matter how large or small - donate today! Read more

Donate