Women are five to ten times more likely to develop Deep Vein Thrombosis (DVT) when pregnant than other women of the same age, and 20 times more likely in the six weeks after birth, with thrombosis recognised as the leading cause of maternal deaths in the developed world.

Anella, now mother to three healthy girls, was shocked to discover her family history of thrombosis made her especially susceptible to thrombosis when pregnant.

“Listening to how I needed to be injected every day during my pregnancy was the last thing I had expected to hear and my worst nightmare!” Anella

During pregnancy, the level of blood-clotting proteins increases, while the level of anti-clotting proteins decreases. Our researchers are working to understand why this is, to enhance our understanding of pregnancy-related thrombosis and its causes.

Scientists are increasingly looking at understanding the expression of genes – or decoding our DNA! MicroRNAs are small molecules that influence the regulation of gene expression.

Perth Blood Institute researchers have discovered that these microRNAs play a role in the ability of the blood to clot. This is an exciting discovery that will help us to develop treatments for pregnancy-related thrombosis.

We need your help! Your support will assist us to further understand the causes, by enabling us to map oestrogen-responsive microRNAs to further decipher the role of microRNA’s in pregnancy-related thrombosis.

Help us to reduce the incidence of thrombosis in women by making a donation to this life-saving research.

While DVT during and after pregnancy is rare, it is important to be aware that your risk rises when you are expecting, so it is vital to be able to recognise the symptoms.

Read Anella's story.

To find out more about pregnancy and thrombosis.

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