Our clinical trials Clinical trials APMAT1 (Microangiopathic Thrombocytopenia; Thrombotic Thrombocytopenic Pupura; Atypical Hemolytic Uremic Syndrome - Recruitment: OPEN) Project Title A multicentre, observational, prospective study of the current practice in major centres in Australia and New Zealand for achieving haemostasis in consecutive patients who present with significant haemorrhage, thromboembolism or urgent surgery whilst on new or established oral anticoagulants. Official Title A multicentre, observational, prospective study of the current practice in major centres in Australia and New Zealand for achieving haemostasis in consecutive patients who present with significant haemorrhage, thromboembolism or urgent surgery whilst on new or established oral anticoagulants. Project Summary This is an observational study to document in major centres in Australia and New Zealand the current practice for achieving haemostasis in patients who present with significant haemorrhage, thromboembolism or require anticoagulant reversal for urgent surgery and/or a procedure whilst on new (dabigatran, rivaroxaban, or apixaban) or established (warfarin) oral anticoagulants. The duration of the study is 42 months. Blood Disorder Microangiopathic Thrombocytopenia (including Thrombotic Thrombocytopaenic Pupura and Atypical Hemolytic Uremic Syndrome) Patient Recruitment Details Patient recruitment status: Open Number of Patients 300 participants. Supporting Organisations Asian-Pacific Microangiopathic Thrombocytopenia Network