Current research projects Research collaborations PBI PBI research collaborations Due to the complexity and rarity of blood disorders, a collaborative effort is required in collecting samples for vital research. PBI collaborates with a large network of national and international partners to establish important disease biobanks. These collaborative networks also conduct research for the standardisation of critical diagnostic assays for rare disease and associated methodologies to expedite disease diagnosis. Translational research collaborations Our Translational Research Team’s current collaboration projects are outlined below. Project Partner(s) Asia-Pacific Microangiopathic Thrombocytopenia Network (APMAT) See APMAT for details. Novel nucleic acid-based biomarkers for thrombotic disorders and in undruggable/difficult to drug cancers Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Australian National University miRNA Regulation of Coagulation Factors Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Anticoagulant Reversal Events Study (ARES) See ARES for details. Large Immune Complex and their role in thrombosis Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Burnett Institute Anti-thrombin aptamer Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Our Translational Research Team’s previous collaboration projects are outlined below. Factor 8 Exon Skipping as a Potential Therapy for Haemophilia A Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Platelet research collaborations Our Platelet Research Team has a wide network of research collaborators, locally and overseas. These scientists are world experts in their fields, and their contributions are instrumental in our multidisciplinary studies - contributing specialist techniques, knowledge and skills. They are co-investigators on many of our projects, and also co-supervise several higher-degree graduate students (Masters, Honours and PhDs). The Platelet Research Team’s collaboration projects are outlined below. Project Partner(s) The investigation of pancreatic cancer-derived factors that contribute to cancer-associated thrombosis Curtin University - School of Pharmacy and Biomedical Sciences Investigation of Novel Biomarkers for Pancreatic Cancer Curtin University - School of Pharmacy and Biomedical Sciences Targeting platelets in pancreatic cancer therapy Curtin University - School of Pharmacy and Biomedical Sciences The role of Factor Xa inhibitor and ADAM10 activity on amyloid precursor protein processing in platelet, and dementia risk (co-investigator, Prof Gardiner, ANU) Curtin University - School of Pharmacy and Biomedical Sciences Investigating a role for the γ-Secretase enzyme in human derived induced microglia-like cells Curtin University - School of Pharmacy and Biomedical Sciences The significance of melanoma-derived exosomes in endothelial dysfunction and metastasis Curtin University - School of Pharmacy and Biomedical Sciences Investigating the Functional Role of ORP1-S in Cancer Curtin University - School of Pharmacy and Biomedical Sciences Analysis of Neutrophils in the Elderly Environment Curtin University - Curtin Health Innovation Research Institute Several platelet-related studies as well as dementia-related projects Australian National University - John Curtin School of Medical Research Platelet/cancer studies with a study on platelet/pregnancy in the pipeline Royal College of Surgeons in Ireland For more information on PBI research collaborations, please contact our research division.