PBI Research Collaborations

Due to the complexity and rarity of blood disorders, a collaborative effort is required in collecting samples for vital research. PBI collaborates with a large network of national and international partners to establish important disease biobanks. These collaborative networks also conduct research for the standardisation of critical diagnostic assays for rare disease and associated methodologies to expedite disease diagnosis.

Translational Research Collaborations

Our Translational Research Team’s collaboration projects are outlined below.

Project	Partner(s)
Asia-Pacific Microangiopathic Thrombocytopenia Network (APMAT)	See APMAT for details.
Factor 8 Exon Skipping as a Potential Therapy for Haemophilia A	Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics
Novel nucleic acid-based biomarkers for thrombotic disorders and in undruggable/difficult to drug cancers	Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Australian National University
miRNA Regulation of Coagulation Factors	Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics
Anticoagulant Reversal Events Study (ARES)	See ARES for details.
Large Immune Complex and their role in thrombosis	Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics Burnett Institute
Anti-thrombin aptamer	Murdoch University - Centre for Molecular Medicine and Innovative Therapeutics

Platelet Research Collaborations

Our Platelet Research Team has a wide network of research collaborators, locally and overseas. These scientists are world experts in their fields, and their contributions are instrumental in our multidisciplinary studies - contributing specialist techniques, knowledge and skills. They are co-investigators on many of our projects, and also co-supervise several higher-degree graduate students (Masters, Honours and PhDs).

The Platelet Research Team’s collaboration projects are outlined below.

Project	Partner(s)
The investigation of pancreatic cancer-derived factors that contribute to cancer-associated thrombosis	Curtin University - School of Pharmacy and Biomedical Sciences
Investigation of Novel Biomarkers for Pancreatic Cancer	Curtin University - School of Pharmacy and Biomedical Sciences
Targeting platelets in pancreatic cancer therapy	Curtin University - School of Pharmacy and Biomedical Sciences
The role of Factor Xa inhibitor and ADAM10 activity on amyloid precursor protein processing in platelet, and dementia risk (co-investigator, Prof Gardiner, ANU)	Curtin University - School of Pharmacy and Biomedical Sciences
Investigating a role for the γ-Secretase enzyme in human derived induced microglia-like cells	Curtin University - School of Pharmacy and Biomedical Sciences
The significance of melanoma-derived exosomes in endothelial dysfunction and metastasis	Curtin University - School of Pharmacy and Biomedical Sciences
Investigating the Functional Role of ORP1-S in Cancer	Curtin University - School of Pharmacy and Biomedical Sciences
Analysis of Neutrophils in the Elderly Environment	Curtin University - Curtin Health Innovation Research Institute
Several platelet-related studies as well as dementia-related projects	Australian National University - John Curtin School of Medical Research
Platelet/cancer studies with a study on platelet/pregnancy in the pipeline	Royal College of Surgeons in Ireland

For more information on PBI research collaborations, please contact our research division.

Latest

Pregnancy Appeal
George's Story

For years George had known his white blood cell count was too high, but as it was just outside the normal range. After being referred to Professor Baker, George was diagnosed with chronic lymphocytic leukaemia (CLL). He joined a clinical trial in August 2015 and two years later, George was completely free of CLL and leading a normal lifestyle.
Clinical Research Fellowship

The Perth Blood Institute (PBI) conducts medical research into blood disorders, including their causes, prevention and treatment options; facilitates access to high quality clinical trials for people affected by blood disorders; and provides information about blood disorders to patients and their families.
Feedback

APTIN

Asia Pacific Thrombosis and Thrombocytopenia Network (APTIN) is a collaborative consortium of leading haematology centres in the Asia Pacific region.

Accessibility
COVID-19 and Thrombosis

The International Society of Thrombosis and Haemostasis has released information on COVID-19 and thrombosis. Here are the important facts; Having a blood clot does not increase your risk of acquiring COVID-19. Taking anticoagulants (blood-thinning medication) for a blood clot disorder also does not increase your risk of acquiring COVID-19.
Elie's Story

When Elie was a young, fit and healthy 22-year-old he noticed a lump in the side of his neck. He went to his GP complaining of fatigue, insomnia, and severe itching. After being misdiagnosed with glandular fever and then a mystery virus, he received a call from his doctor.
Privacy Policy

THE PERTH BLOOD INSTITUTE LIMITED ABN: 24164941815 (trading as Perth Blood Institute) takes your privacy seriously. We respect and uphold your right to privacy protection under the Australian Privacy Principles (APPs), by regulating the way in which we collect, use, disclose, hold and destroy your personal information. This Privacy Policy covers all personal information held by us.
Research Team Awarded DARF Dementia Grant

Perth Blood Institute is pleased to announce it is the recipient of the Norma Beaconsfield Project Grant, awarded by the Dementia Australia Research Foundation (DARF). This grant will allow the Platelet Research Team to continue important investigations into the effect of blood-thinning medication on dementia risk.
Clinical Research Fellowship

The Perth Blood Institute (PBI) conducts medical research into blood disorders, including their causes, prevention and treatment options; facilitates access to high quality clinical trials for people affected by blood disorders; and provides information about blood disorders to patients and their families.
COVID-19 - Impact on blood transfusions and blood donations

Some members of the community may be concerned about the potential transmission of the COVID-19 virus through blood products, such as through blood transfusions. If you rely on blood products, you should feel confident to continue to receive them.
George's Story

For years George had known his white blood cell count was too high, but as it was just outside the normal range. After being referred to Professor Baker, George was diagnosed with chronic lymphocytic leukaemia (CLL). He joined a clinical trial in August 2015 and two years later, George was completely free of CLL and leading a normal lifestyle.
Understanding platelet dysfunction in Chronic Lymphocytic Leukemia

This project aims to examine platelets from healthy and Chronic Lymphocytic Leukemia (CLL) individuals to better understand the mechanisms underpinning platelet dysfunction in CLL, which may lead to better anti-cancer treatment strategies.
Key staff

Perth Blood Institute

Your donation can help PBI to fund vital translational research into blood disorders including thrombosis and haemophilia; support a clinical research investigation into the development of a new treatment or intervention; or help us develop educational programs to foster the next generation of career haematologists. Read more

Donate Fundraise

Translational Research Collaborations

Project

Partner(s)

Platelet Research Collaborations

Project

Partner(s)