Our clinical trials Clinical trials CADENCE (Cold Agglutinin Disease - Recruitment: OPEN) Project Title CADENCE Official Title Cold Agglutinin Disease Real World Evidence Registry Project Summary Cold agglutinin disease (CAD) is a rare condition. Prospective longitudinal data in large populations are therefore limited. The aim of this registry is to prospectively collect longitudinal data in order to better understand patient and clinical characteristics, disease progression, complications, treatment impact, and patient-reported outcomes. This registry will also improve the understanding of the natural history of CAD and will help raise awareness of CAD and its treatment. Blood Disorder Cold Agglutinin Disease Patient Recruitment Details Patient recruitment status: Open Number of Patients The registry targets to enrol approximately 700 patients (globally).