CANOVA (Multiple Myeloma - Recruitment: CLOSED)

Project Title

A Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma (CANOVA).

Official Title

A Phase III, Multicenter, Randomized, Open Label Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma.

Project Summary

A study designed to evaluate the safety and efficacy of venetoclax plus dexamethasone (VenDex) compared with pomalidomide plus dexamethasone (PomDex) in participants with t(11;14)-positive Relapsed or Refractory Multiple Myeloma.

Blood Disorder

t(11;14)-positive Relapsed Multiple Myeloma
Refractory Multiple Myeloma

Patient Recruitment Details

Patient recruitment status: closed

Number of Patients (Globally)

244 participants.

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Inherited Thrombophilias

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Graham Wild

Graham Wild, a passionate 15-year-old boy with a deep love for nature and animals, had dreams of running an animal sanctuary. After returning from a trip to see his dad, Graham started to have trouble breathing and his health rapidly deteriorated. Despite urgent medical attention, his heart stopped, and he couldn't be revived. Graham's mother Kathryn would like to share his story. Read more