Clinical trials Our clinical trials Hokusai VTE Cancer (Venous Thromboembolism) Project Title Cancer Venous Thromboembolism (VTE). Official Title A Phase 3b, Prospective, Randomized, Open-label, Blind Evaluator (PROBE) Study Evaluating the Efficacy and Safety of (LMW) Heparin/Edoxaban Versus Dalteparin in Venous Thromboembolism Associated With Cancer. Project Summary The primary objective is to demonstrate the non-inferiority of edoxaban (preceded by a short course of LMWH) compared with dalteparin for the prevention of the combined outcome of recurrent venous thromboembolism (VTE) or major bleeding in subjects with VTE associated with cancer during a 12-month study period. If non-inferiority is established, LMWH/edoxaban will be compared with dalteparin for superiority. Blood Disorder Venous Thromboembolism Deep Vein Thrombosis Pulmonary Embolism Cancer Patient Recruitment Details Patient recruitment status: Closed Number of Patients (globally) 1046 participants. Back to Archived Projects...