News and events Publications Research Publications Since its establishment in 2013, PBI has been active in delivering research papers and oral presentations to the scientific and medical community. PBI has been invited to deliver diverse presentations and act as session chair at conferences and meetings; and has been successful in securing a significant number of awards. Additionally, PBI has been recognised for our high scoring and accepted abstracts, a significant achievement for an emerging research institute. Research Papers 2019 Ho KM, Rao S, Honeybul S, Zellweger R, Wibrow B, Lipman J, Holley A, Kop A, Geelhoed E, Corcoran T, Misur P, Edibam C, Baker RI, Chamberlain J, et al. A Multicenter Trial of Vena Cava Filters in Severely Injured Patients. N Engl J Med. 2019 Jul 25; 381(4):328-337. Favaloro EJ, Gilmore G, Arunachalam S, Mohammed S, Baker RI. Neutralising rivaroxaban induced interference in laboratory testing for lupus anticoagulant (LA): A comparative study using DOAC Stop and andexanet alfa. Thromb Res. 2019 Aug; 180:10-19. 2018 Wines BD, Tan CW, Duncan E, McRae S, Baker RI, Andrews RK, et al. Dimeric FcγR ectodomains detect pathogenic anti-platelet factor 4-heparin antibodies in heparin-induced thromobocytopenia. J Thromb Haemost. 2018 Dec; 16 (12):2520-2525. 2017 Hughes QW, Le BT, Gilmore G, Baker RI, Veedu RN. Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties. Molecules. 2017 Oct 19; 22 (10). pii: E1770. Tay JW, James I, Hughes QW, Tiao JY, Baker RI. Identification of reference miRNAs in plasma useful for the study of oestrogen-responsive miRNAs associated with acquired Protein S deficiency in pregnancy. BMC Res Notes. 2017 Jul 25; 10(1):312. Tay JW, Tiao J, Hughes Q, Jorritsma J, Gilmore G, Baker R. Circulating microRNA as thrombosis sentinels: Caveats and considerations. (2017) Seminars in Thrombosis and Hemostasis. Pasi KJ, Fischer K, Ragni M, Nolan B, Perry DJ, Kulkarni R, Ozelo M, Mahlangu J, Shapiro AD, Baker RI, Bennett CM, et al. Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B. Thromb Haemost. 2017 Feb 28; 117(3):508-518. Quon DV, Klamroth R, Kulkarni R, Shapiro AD, Baker RI, Castaman G, et al. Low bleeding rates with increase or maintenance of physical activity in patients treated with recombinant factor VIII Fc fusion protein (rFVIIIFc) in the A-LONG and Kids A-LONG Studies. Haemophilia. 2017 Jan; 23(1): e39-e42. 2016 Tay, JW, Tiao, J, Hughes, Q, Gilmore, G and Baker, R (2016) Therapeutic Potential of miR-494 in Thrombosis and Other Diseases: A Review. (2016) Australian Journal of Chemistry 69 (10) · January 2016 Mahlangu J, Kuliczkowski K, Karim FA, Stasyshyn O, Kosinova MV, Lepatan LM, Skotnicki A, Boggio LN, Klamroth R, Oldenburg J, Hellmann A, Santagostino E, Baker RI, Fischer K, et al; AFFINITY Investigators. Efficacy and safety of rVIII-SingleChain: results of a phase 1/3 multicenter clinical trial in severe hemophilia A. Blood. 2016 Aug 4; 128 (5):630-7. 2015 Qiao J, Al-Tamimi M, Baker RI, Andrews RK, et al. The platelet Fc receptor, FcγRIIa. Immunol Rev. 2015 Nov; 268(1):241-52. Metharom P, Berndt MC, Baker RI, Andrews RK. Current state and novel approaches of antiplatelet therapy. Arterioscler Thromb Vasc Biol. 2015 Jun; 35(6):1327-38. 2014 Baker RI, McGregor SR. Does preoperative laboratory monitoring of antithrombotic therapy avoid adverse outcomes in patients undergoing surgery or regional anaesthesia? Anaesth Intensive Care. 2014 Sep; 42(5):555-7. 2013 Powell JS, Pasi KJ, Ragni MV, Ozelo MC, Valentino LA, Mahlangu JN, Josephson NC, Perry D, Manco-Johnson MJ, Apte S, Baker RI, Chan GC, et al; B-LONG Investigators. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med. 2013 Dec 12;369 (24):2313-23. Tay JW, Romeo G, Hughes QW, Baker RI. Micro-ribonucleic Acid 494 regulation of protein S expression. J Thromb Haemost. 2013 Aug; 11(8):1547-55. Kuter DJ, Bussel JB, Newland A, Baker RI, Lyons RM, et al. Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy. Br J Haematol. 2013 May; 161(3):411-23. Awards/Grants/Scholarships 2019 Mr Omar Elaskalani was awarded the prestigious THANZ Scientific Medal for best abstract at the Annual Scientific Meeting - Blood 2019. 2018 Professor Ross Baker, together with a team of researchers, including The Australian National University (ANU), was awarded a four-year NHMRC Project Grant entitled “Pathobiology that causes fatal thrombosis in HIT” starting in 2018. In 2018 Dr. Jim Tiao and Professor Ross Baker, and alumni member Dr. Quintin Hughes, were the recipients of grant funding from the John Lloyd Clinical Excellence Fund, for a project to investigate novel gene therapeutics in the treatment of Haemophilia A. For our work on Haemophilia A, Dr. Jim Tiao was a recipient of the AHCDO Grant in 2018 for his abstract presented at the Annual Scientific Meeting - Blood 2018. 2017 Researchers have also been successful in winning conference presentation awards. In 2017, PhD candidate Ms Jiayin Tian received a 2017 runner-up prize in the THANZ Scientific Medal conference session. Ms Tian also received several travel awards for conference presentations, including THANZ scientific and education trust travel grant, Werfen Travel grant and the Murdoch University graduate research conference travel grant. In 2017, Mr. Michael Menezes was a recipient of best poster prize – scientific, at the same conference. In 2017 Dr. Jim Tiao and Professor Ross Baker, and alumni member Dr. Quintin Hughes, were the recipients of grant funding from the John Lloyd Clinical Excellence Fund, for a project to investigate novel gene therapeutics in the treatment of Haemophilia A. 2016 In 2016 researcher Dr Jasmine Tay (alumni) was awarded the inaugural THANZ Scientific Medal for best abstract at the Annual Scientific Meeting – HAA 2016. In 2016 Dr. Jim Tiao and Professor Ross Baker, and alumni member Dr. Quintin Hughes, were the recipients of grant funding from the John Lloyd Clinical Excellence Fund, for a project to investigate novel gene therapeutics in the treatment of Haemophilia A.