Our research focuses on the discovery and application of new science that aims to address the unmet medical needs of patients who currently suffer with incurable blood disorders. Our ongoing projects are focused on examining the changes in blood cell components which increase the likelihood of developing blood clots.
Details on our current research projects, including each project's current recruitment status, are provided below. If you are interested in participating in any of our projects, please visit Participate in a research project.
A strategy towards novel biomarker discovery and personalised medicine. Read more
This project aims to examine platelets from healthy and Chronic Lymphocytic Leukemia (CLL) individuals to better understand the mechanisms underpinning platelet dysfunction in CLL, which may lead to better anti-cancer treatment strategies. Read more
This project aims to restore Factor VIII protein functions by correcting the mutations with exon skipping as a novel therapeutic. Read more
This project aims to develop a method for screening patient samples for specific populations of anti-ADAMTS13 autoantibodies and determining their role in thrombotic disorders, including Thrombotic Thrombocytopaenic Purpura onset and stroke. Read more
This study aims to utilise this knowledge to map oestrogen/hormone-responsive microRNAs, and decipher the role(s) of microRNAs in the regulation of haemostasis and thrombotic disorders. Read more
This project aims to examine FXa inhibition on the risk of cognitive decline and investigates the molecular mechanisms underlying this association. Read more